A magnitude 6.4 struck the Turkey-Syria border region on Monday, the European Mediterranean Seismological Centre (EMSC) said.
At least three people have died and over 200 were injured, according to Turkish officials.
The quake hit near Defne in the district of Samandag but it was felt as far as Jordan, Israel, and Egypt.
“We had just arrived in Gaziantep when we felt the tremor. Our car started shaking — for about 10 seconds. We immediately thought it was an earthquake because we use an alert app. And then we saw people had run out of buildings here in the city centre,” DW correspondent Julia Hahn said from the scene.
“That’s when we knew it was a powerful one.”
The initial quake was followed by a second, magnitude 5.8 tremor.
Lutfu Savas, the mayor for Hatay said a number of buildings have collapsed, trapping people who had either returned to homes or were trying to move furniture from damaged homes.
Abdel Kafi, a Syrian activist in north-west Syria said, “It was strong like the first one but did not last long… it scared people and people rushed to the streets.”
The event triggered panic and a stampede in Syria, with some people jumping from buildings, according to the UK-based Syrian Observatory for Human Rights.
It comes two weeks after two major earthquakes devastated the same region and left at least 47,000 dead.
Turkey’s Disaster and Emergency Management Authority (AFAD) said more than 6,000 aftershocks had been recorded since the 7.8-magnitude quake hit Turkey and Syria on February 6.
US promises Turkey to help ‘as long as it takes’
Hours before the latest earthquake, US Secretary of State Antony Blinken, who was on a visit to Turkey, vowed the American government would help “for as long as it takes.”
Binken pledged another $100 million in disaster assistance after a helicopter tour of the devastated Hatay province.
On Monday, Blinken met his Turkish counterpart Mevlut Cavusoglu and Turkish President Recep Tayyip Erdogan.
Erdogan said construction work on nearly 200,000 apartments in 11 earthquake-hit provinces of Turkey would begin next month.
Blinken also praised the work of the Syrian White Helmets and the search-and-rescue teams who assisted quake victims in Syria’s opposition-held areas.
Germany’s Steinmeier calls for ‘enduring’ aid to quake victims
Also on Monday, German President Frank-Walter Steinmeier called on Germans to show “enduring solidarity” with those affected by earthquakes in Syria and Turkey.
“Our humanity remains in demand even after images from the earthquakes are replaced in the daily news,” Steinmeier said.
He was speaking at an event in Berlin to commemorate the quake victims, organised by the Turkish Community in Germany and the VDSH association of German-Syrian aid organisations.
Germany has already sent 82 tonnes of relief supplies to the region and was planning to contribute to an EU shipment of relief supplies.
The country has also contributed €26 million ($27 million) in humanitarian assistance for people in Syria.
The aid is on top of German search-and-rescue teams who helped with relief efforts in the quake area.
This article was originally published on DW.